A Fioricet tablet may include acetaminophen, caffeine, and butalbital. Acetaminophen is effective against both pain and fever, making it a versatile drug. To put it simply, butalbital belongs to the barbiturate category of drugs.

Tension headaches are alleviated because muscle spasms are reduced. Caffeine is an effective stimulant because of its effect on the brain and neurological system. It does this by reducing the tension in the smooth muscle lining the inside of blood arteries.
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